Ribetril A
About Ribetril A Technology

Asiros had discovered a uniquely Polyphenol Bioactive Compound, called Ribetril A, found in specific varieties of redcurrants and blackcurrants. It is patented by Asiros, Denmark.

Ribetril A Technology

Ribetril A –.



Ribetril A functional benefits is entirely differently from traditional energy-boosting supplements like Q-10, NADH and alpha-ketoglutarate (AGK). Ribetril A works differently, by optimizing the mitochondria energy output in 2 fundamental ways: bringing to a whole new level of combined bioactivity.
  • By stimulating the mitochondria production, increase the amount of mitochondria formation. More mitochondria can produce more cellular energy in the form of ATP in our body.  An analogy of car engine, by upgrading the number of cylinders in an engine, more power can be produce.
  • By improving the mitochondrial spare respiratory capacity* i.e. increasing the amount of extra ATP that can be produced by oxidative phosphorylation in case of a sudden increase in energy demand. 
Benefits of Ribetril A
  • Increase energy level by increasing number of mitochondrial
  • Improve stamina, endurance and reduce fatique
  • Improve muscles recovery from sports activity
  • Improve alertness and stay sharp
  • Sustain effect
  • Youthful glowing skin and anti wrinkle
Scientific Evidences

1) Seahorse Bioscience XF Cell Mito Stress Test.

Ribetril A Improved Mitochondrial Stress Capacity in Muscles Cells
*Spare Respiratory Capacity and basal respiration was tested in the Seahorse BioScience XF Cell Mito Stress Test

Result:
Ribetril A provide more energy available for muscles upon demand. Results in higher stamina, endurance and reduce fatique.

Information

 
WHAT IS Spare Respiratory Capacity (SRC)
  • In aerobic cells, the majority of ATP is produced by oxidative phosphorylation. This process takes place in the mitochondria.
  • The term spare respiratory capacity is used to describe the amount of extra ATP that can be produced by oxidative phosphorylation (OP) in case of a sudden increase in energy demand.
    - The differences between ATP produced by OP at basal and that at maximal activity is terms `spare respiratory capacity’.
The Study
  • Copenhagen University: Muscle cell mitochondrial stress response study.
  • Mitochondrial Oxygen Consumption Rate in muscle cells exposed to Ribetril A in two doses as compared to untreated control.
  • Mitochondrial Oxygen Consumption Rate (OCR, pmol/min) in C2C12 cells exposed to ribetril A.
Results


Result Show :
  • Ribetril A treated muscle cells demonstrated a higher basal level of oxygen consumption as well as a higher Spare Respiratory Capacity.
2) COOPER TEST – Improved Sports Performance
  • Endurance exercise training increases the mitochondrial enzymes capacity and total mitochondrial volume, therefore, increase the athlete’s performance potential.
  • Ribetril A stimulates mitochondrial production and improve the stress-response.
Result:
Ribetril A improved performance for highly competitive sports. 


A Pilot Cooper test was conducted.

Information
WHAT IS Cooper Test:
Is it a physical fitness test. The point of the test is to run as far as possible within 12 minutes.

Ribetril A, Cooper Test

  • 5 athletes with a stable and high level of training
  • For 3 weeks, the athletes took a daily dose of Ribetril A, active component of MitoActive and performed a Cooper every week.


Performance in repeated Cooper tests (relative change). 
*p<0.05    **p<0.001
Results shows as follows
  • A significant increase in performance of 1.8% (p<0.05) compared to baseline performance was observed already after one week of intake of Ribetril A, MitoActive™. 
  • After 2 and 3 weeks, a further increase in performance of 4.2% (p<0.001) and 4.5% (p<0.001) respectively was observed.

3) The Effect of Ribetril A, MitoActive™ versus placebo on the urine metabolome in trained athletes during a 21 days intense exercise schedule 
  • Placebo-controlled Clinical Trial in 31 highly trained athletes
  • Performed at Copenhagen University
  • Standardized intensified training schedule during the treatment period of 3 weeks with a single daily oral dose of Ribetril A, MitoActive™ or Placebo.
  • Urine samples taken on day 1 (before treatment) and on day 21.
Result:
  • Reduce muscle soreness,
  • Faster muscles recovery.

Results
  • Ribetril A, MitoActive™ prevented an increase in lactic acid seen in the placebo group indicating a decrease of anaerobic metabolism (P ≤ 0.0001).
  • Ribetril A, MitoActive™ prevented a fall in pyruvic acid seen in the placebo group indicating a better maintenance of aerobic metabolism (P ≤ 0.01).
Information
  • Lactic acid and other metabolites build up, result in muscles soreness.
  • Reduce lactic acid an indication or reduce anaerobic, better aerobic metabolism, reduce lactate and other metabolites buildup.
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